Gene description for HSPA1A
Gene name	heat shock protein family A (Hsp70) member 1A
Gene symbol	HSPA1A
Other names/aliases	HEL-S-103 HSP70 HSP70-1 HSP70-1A HSP70-2 HSP70.1 HSP70.2 HSP70I HSP72 HSPA1
Species	Homo sapiens
Experiment description of studies that identified HSPA1A in Liver cancer cells
1 Experiment ID 2437 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name CSQT-2 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
2 Experiment ID 2438 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name HCC-LM3 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
3 Experiment ID 2439 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name HepG2 Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
4 Experiment ID 2440 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 29335551    Organism Homo sapiens Experiment description Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Authors Fang T, Lv H, Lv G, Li T, Wang C, Han Q, Yu L, Su B, Guo L, Huang S, Cao D, Tang L, Tang S, Wu M, Yang W, Wang H. Journal name Nat Commun Publication year 2018 Sample Liver cancer cells Sample name MHCC-97L Isolation/purification methods Filtration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray qRT-PCR EV-TRACK -
5 Experiment ID 3088 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
6 Experiment ID 3089 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
7 Experiment ID 3090 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
8 Experiment ID 3091 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
9 Experiment ID 3092 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 3093 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 3094 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 3095 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
13 Experiment ID 3098 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
14 Experiment ID 3099 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
15 Experiment ID 3100 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
16 Experiment ID 3101 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name 97H Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
17 Experiment ID 3102 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
18 Experiment ID 3103 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
19 Experiment ID 3104 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
20 Experiment ID 3105 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36631249    Organism Homo sapiens Experiment description S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Authors Wang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO. Journal name Gut Publication year 2023 Sample Liver cancer cells Sample name PLC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
21 Experiment ID 2476 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -
22 Experiment ID 2477 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -